Hey racermp,
Not sure if you ever figured out your issue with the P2421 code on the N55 but my '11 335i just fell victim to the same problem. I went ahead and replaced the fuel tank breather valve connected to the intake throttle body, reset the code, and two days later it's back. Only thing I can think is perhaps the DMTL pump could be the culprit. I'm at my wits end and you are the ONLY person I can find that's experienced the same issue with the N55.
Did you ever squash the gremlin in yours?
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